A placental clock controlling the length of human pregnancy,[url=http://www.masterclass-detailing.co.uk/category/ralph-lauren-polo/]Ralph Lauren Polo[/url]
AbstractWe report the existence of a 'placental clock',[url=http://www.article-web.co.uk/category/hermes-belts/]Hermes Belts[/url], which is active from an early stage in human pregnancy and determines the length of gestation and the timing of parturition and delivery. Using a prospective, longitudinal cohort study of 485 pregnant women we have demonstrated that placental secretion of corticotropin releasing hormone (CRH) is a marker of this process and that measurement of the maternal plasma CRH concentration as early as 16 weeks of gestation identifies groups of women who are destined to experience normal term, preterm or post term delivery. Further, we report that the exponential rise in maternal plasma CRH concentrations with advancing pregnancy is associated with a concomitant fall in concentrations of the specific CRH binding protein in late pregnancy, leading to a rapid increase in circulating levels of bioavailable CRH at a time that coincides with the onset of parturition, suggesting that CRH may act directly as a trigger for parturition in humans.

[url=http://vote.qdxiaoluohao@#$%&/dzx/forum.php?mod=viewthread&tid=5652630&extra=]Hermes Birkin Bag A Mixed Bag with Limited Potential Impact[/url]

[url=http://www.ijiaren@#$%&/blog/?uid-486-action-viewspace-itemid-3084]Hermes Birkin Bag 5 million deal from UK's Network Rail[/url]

[url=http://www.centralepiecesauto@#$%&/spip.php?article8]Hermes Handbags Adams County News[/url]

[url=http://www.ijiaren@#$%&/blog/?uid-486-action-viewspace-itemid-3079]Hermes Handbags 7 Home Remedy Tips To Perk Up Your Home Decor[/url]

[url=http://www.ijiaren@#$%&/blog/?uid-486-action-viewspace-itemid-3081]Hermes Wallet 11 soldiers wounded in Philippines as communist re[/url]